Lanthipeptide

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Lanthipeptide. Ad Shuttle vector pESAC13 vector Streptomyces BAC library Antibiotic research. The characteristic lanthionine moiety in lexapeptide is formed by three proteins LxmK LxmX and LxmY which are distinct from enzymes known to be involved in lanthipeptide biosynthesis. Keyzers bc and Margaret A. Class III lanthipeptide clusters like labyrinthopeptin FN178622 42.

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While lanthipeptide biosynthetic gene clusters can be identified by the presence of characteristic enzymes involved in the post-translational modification of these peptides locating the precursor peptides encoded within these clusters is challenging due to their short length and high sequence variability which limits the high-throughput exploration of lanthipeptide precursor peptides. Meindl et al 2010. Lasso peptides are short peptides containing an N-terminal macrolactam macrocycle ring through which a. Class II lanthipeptide clusters like mutacin II U40620 42. Brimble abf a. Harvey bc Matthew B.

Lanthipeptides are ribosomally synthesized and post-translationally modified peptides RiPPs that are generated from a precursor peptide containing an N-terminal leader peptide and a C-terminal core peptide.

Class IV lanthipeptide clusters like venezuelin HQ328852 42. Meindl et al 2010. Buzhe Xu ab Emma J. A generic designation for lanthipeptide biosynthetic proteins. While lanthipeptide biosynthetic gene clusters can be identified by the presence of characteristic enzymes involved in the post-translational modification of these peptides locating the precursor peptides encoded within these clusters is challenging due to their short length and high sequence variability which limits the high-throughput exploration of lanthipeptide precursor peptides. Stott de Jean F.

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Class I lanthipeptides are synthesized by two different enzymes a dehydratase LanB and a cyclase LanC Lan is a generic designation for lanthipeptide biosynthetic proteins. Aitken c Benjamin P. The post-translational modification rea. Brimble abf a. Ad Shuttle vector pESAC13 vector Streptomyces BAC library Antibiotic research.

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